Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury (SCI). Those with an SCI are two to five times more likely to die prematurely than people without a spinal cord injury, with worse survival rates in low- and middle-income countries. Dynamic aerobic requires integrated physiologic responses across the musculoskeletal, cardiovascular, autonomic, pulmonar…
Well known experts in the field of Chronobiology from around the world, provide an integrative view of the state of the art of circadian biology. At present, genetic and epigenetic interaction of regulatory pathways among circadian oscillators, metabolic networks, cellular differentiation and neuronal communication are subject of intense scrutiny. The book is organized in three sections: The fi…
This book gives insight into the mechanism of the immune system and the influence of the environment on earth. Further, the book explains the changes that occur in our immune system in the absence of gravity and their fundamental consequences. Several limiting factors for human health and performance in microgravity have been clearly identified as an unacceptable risk for long-term and i…
An overview of all the available literature on the various aspects of the regulation of the cardiovascular system`s function and physiology by the adrenergic neurohormonal system, i.e. the catecholamines norepinephrine and epinephrine. Although there are several books describing the adrenergic system`s biology, physiology and pharmacology, and also several excellent books on cardiovascular phys…
This book provides a comprehensive review of the latest advances in translational pain and itch research, and presents the cutting-edge developments in the study of our two principal, yet most mysteries sensations. Despite the slow progress in the discovery of effective therapies for chronic pain and pruritus, scientists around the globe now have a better understanding of why and how these cond…
JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
This volume discusses membrane potential imaging in the nervous system and in the heart and modern optical recording technology. Additionally, it covers organic and genetically-encoded voltage-sensitive dyes; membrane potential imaging from individual neurons, brain slices, and brains in vivo; optical imaging of cardiac tissue and arrhythmias; bio-photonics modelling. This is an expanded and fu…