The association between chronic inflammation and bone destruction has long been recognized, but the molecular bases of the underlying mechanisms were identified only 20 years ago with the discovery of the essential role of the RANK/RANKL axis in bone and immune cell physiopathology
Vaccines have been one of the most important medical discoveries of the last three centuries. Thanks to their development, millions of deaths have been avoided. Together with improved hygiene and antibiotics, vaccines have significantly contributed to the prolongation of life expectancy in high-income countries to a current average of 85 years, compared to 47 years in 1900. However, the continu…
This book represents the culmination of the efforts of a group of outstanding experts in vasculitis from all over the world, who have endeavored to devote their work to this book by keeping both the text and the accompanying figures and tables lucid and memorable. Here, you will find an amalgam between evidence-based medicine to one based on eminence, through an exciting combination of original…
This book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background i…
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It…
"This book offers a description of bioinformatics techniques as they are applied to immunology, including a succinct account of the main biological concepts for students and researchers with backgrounds in mathematics, statistics, and computer science as well as explanations of the new data-driven algorithms in the context of biological data that will be useful of immunologists, biologists, and…
This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; co…
Inflammation is the very natural process of our body; it does its work immediately and smoothly along with lots of helpers. Inflammation is linked to immune system as acute inflammatory or pro-inflammatory phase through macrophage activation. This book is for researchers and scholars in the field of life sciences and medical sciences. The book contains all inflammatory sources around the world.…
Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.