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Found 7 from your keywords: subject="Medical Genetics,"
cover
The Initiation of DNA Replication in Eukaryotes
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Daniel L. Kaplan

​Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The process of DNA replication needs to be precisely regulated to ensure that replication of the genome is complete and accurate, but that re-replication does not occur. Errors in DNA replication can lead to genome instability and cancer. The process of repl…

Edition
1
ISBN/ISSN
978-3-319-24696-3
Collation
XII, 563, 3 b/w illustrations, 84 illustrations in colour
Series Title
The Initiation of DNA Replication in Eukaryotes
Call Number
-
cover
The Genetics of Type 2 Diabetes and Related Traits
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Jose C. Florez

This book presents the state of the art of type 2 diabetes genetics, from the process of genetic discovery to its interpretation and clinical application, and illustrates a model for other complex human phenotypes. The first section explores genome-wide association studies, the extension of this method to less accessible phenotypes and the arrival of next-generation sequencing. A further secti…

Edition
1
ISBN/ISSN
978-3-319-01574-3
Collation
XI, 576, 40 b/w illustrations, 13 illustrations in colour
Series Title
The Genetics of Type 2 Diabetes and Related Traits
Call Number
-
cover
Non-coding RNAs in Colorectal Cancer
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SLABY, OndrejCALIN, George A

This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer.This work further provides the…

Edition
1
ISBN/ISSN
978-3-319-42057-8
Collation
VIII, 252
Series Title
Advances in Experimental Medicine and Biology
Call Number
-
cover
The Neuropathology of Huntington’s Disease: Classical Findings, Recent Deve…
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RÜB, Udo, etc

This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correla…

Edition
-
ISBN/ISSN
978-3-319-19285-7
Collation
XIV, 146
Series Title
Advances in Anatomy, Embryology and Cell Biology
Call Number
-
cover
Long Noncoding RNAs: Structures and Functions
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Riki Kurokawa

This book presents a common principle of actions of long noncoding RNAs (lncRNAs) from points of view at the atomic, molecular and cellular levels. At the atomic level, chemical studies of ribonucleic acids explain the chemical behavior of lncRNAs. Structural biological analysis of lncRNAs and its binding proteins also reveal the precise mechanisms of their actions. Molecular biological approac…

Edition
-
ISBN/ISSN
978-4-431-55576-6
Collation
-
Series Title
-
Call Number
-
cover
The Genetics of Type 2 Diabetes and Related Traits
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Jose C. Florez

The first section explores genome-wide association studies, the extension of this method to less accessible phenotypes and the arrival of next-generation sequencing. A further section goes beyond genetics to illustrate how other data sources can help interpret genetic data, such as leveraging population diversity, the correlation of genetic associations with physiological measurements, gene exp…

Edition
-
ISBN/ISSN
978-3-319-01574-3
Collation
XI, 576
Series Title
-
Call Number
-
cover
Long Noncoding RNAs: Structures and Functions
Comment Share
Riki Kurokawa

This book presents a common principle of actions of long noncoding RNAs (lncRNAs) from points of view at the atomic, molecular and cellular levels. At the atomic level, chemical studies of ribonucleic acids explain the chemical behavior of lncRNAs. Structural biological analysis of lncRNAs and its binding proteins also reveal the precise mechanisms of their actions. Molecular biological approac…

Edition
-
ISBN/ISSN
978-4-431-55576-6
Collation
-
Series Title
-
Call Number
-