Glycosyl inositol phospho ceramides (GIPCs) are the major sphingolipids on earth, as they account for a considerable fraction of the total lipids in plants and fungi, which in turn represent a large portion of the biomass on earth. Despite their obvious importance, GIPC analysis remains challenging due to the lack of commercial standards and automated annotation software. In this work, we i…
This Open access book offers updated and revised information on vessel health and preservation (VHP), a model concept first published in poster form in 2008 and in JVA in 2012, which has received a great deal of attention, especially in the US, UK and Australia. The book presents a model and a new way of thinking applied to vascular access and administration of intravenous treatment, and …
This open access illustrated guide focuses on Female Genital Mutilation/Cutting (FGM/C) in children and adolescents. FGM/C comprises all procedures that involve partial or total removal of the external female genitalia or injury to the female genital organs for nonmedical reasons. It is mainly carried out during childhood, before the age of 15. The signs of FGM/C can be subtle, and the ex…
This open access book offers a valuable resource for understanding the correct pathways in the context of sexual disorders, couple reproduction, gender identity dysphoria, conditions for which patients commonly ask for consultation and treatment. Based on clinical evidence, international guidelines and experts experience, practical clinical management strategies are presented for each condition…
This work traces and anticipates past, present and future changes in mental health services to assess the impact both of developments in care, and of the implications of new organisational change. It includes contributions and perspectives of those involved in services at all levels, including service users, to draw upon their experience to give a fuller picture of today and help sketch in tomo…
Many patients with pulmonary complaints fail to improve despite physicians’ best efforts. Sometimes, we ascribe this failure to lack of adherence with therapy, or to the severity of the condition. What we often fail to appreciate, however, is that sometimes the lack of improvement can be explained by the patients' psychological states. The first section of Functional Respiratory Disorders: W…
This book describes the pathophysiological significance of the hemodynamic monitoring parameters available to the clinician and their role in providing reliable and reproducible information on the cardiocirculatory status of a patient in shock. It is explained how measurements of these parameters enable the intensivist to understand the patient’s condition and to make more informed treatment …
This book brings together two important discussions in public health in developing countries: an understanding of the burden of disease, health equity and social determinants of health; and biomathematical models, epidemiological studies and estimation of the direct and indirect cost of disease. The empirical chapters in the first part discuss aspects of disease prevention and health promotion …
This book discusses the interpretation of mechanical ventilator waveforms. Each page shows a screenshot from a real patient and explains one or two messages. It starts with basic information about the waveforms and goes on to address passive and spontaneous ventilation, non-invasive ventilation and specific measurements such as pressure-volume curves and esophageal pressure. Step by step, reade…
This book discusses the interpretation of mechanical ventilator waveforms. Each page shows a screenshot from a real patient and explains one or two messages. It starts with basic information about the waveforms and goes on to address passive and spontaneous ventilation, non-invasive ventilation and specific measurements such as pressure-volume curves and esophageal pressure. Step by step, reade…