Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a varie…
The biological membranes of cellular organization enfold an important group of membrane proteins called the ATPases, which are not only versatile in maintaining chemical gradient and electrical potential across the membrane but also bring metabolites necessary for cell metabolism and drive out toxins, waste products and solutes that otherwise can curb cell functions. ATPases are distributed vir…
This thesis presents a highly innovative study of the ultrafast structural and vibrational dynamics of hydrated phospholipids, the basic constituents of cell membranes. As a novel approach to the water-phospholipid interface, the author studies phosphate vibrations using the most advanced methods of nonlinear vibrational spectroscopy, including femtosecond two-dimensional infrared spectroscopy.…
Ada minat yang sangat besar dan kebutuhan untuk menerapkan membran polimer untuk pemisahan dan pemurnian yang melibatkan pelarut organik, terutama membran difusi larutan dalam aprotik polar dan campurannya dalam industri termasuk bahan kimia halus, farmasi, perminyakan, minyak, dan bioteknologi. Namun, beberapa kelemahan termasuk kinerja yang tidak dapat diprediksi, model karakterisasi yang tid…
Sumber energi utama bagi kehidupan di Bumi adalah energi matahari dari Matahari. Sel mengubah energi radiasi menjadi jenis energi lain. Energi kimia utama yang dihasilkan oleh sel adalah ATP. Pada gilirannya, energi yang dibutuhkan untuk kerja seluler disediakan oleh ATP, mata uang energi sel. Sebagian besar energi kimia ATP dalam sel digunakan untuk (i) kerja mekanis, (ii) proses biosintesis, …
This contributed volume reviews the recent progress in our understanding of membrane transport in yeast including both Saccharomyces cerevisiae and non-conventional yeasts. The articles provide a summary of the key transport processes and put these in a systems biology context of cellular regulation, signal reception and homeostasis. After a general introduction, readers will find review ar…
Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a varie…
This thesis presents a highly innovative study of the ultrafast structural and vibrational dynamics of hydrated phospholipids, the basic constituents of cell membranes. As a novel approach to the water-phospholipid interface, the author studies phosphate vibrations using the most advanced methods of nonlinear vibrational spectroscopy, including femtosecond two-dimensional infrared spectroscopy.…
This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was named P-glycoprotein. It elicits resistance to cytotoxic drugs, chiefly in human tumours, within wh…