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The New Drug Reimbursement Game
The limitations of the non-strategic methods that currently inform the highly contested new drug subsidy game are presented and the relative strengths of PEA are demonstrated. Health technology assessment quantifies both the clinical innovation of a new drug and its financial impact on the health system. Cost effectiveness analysis tests the relationship between the incremental cost and incre…
- Edition
- -
- ISBN/ISSN
- 978-3-319-08903-4
- Collation
- XVI, 248
- Series Title
- -
- Call Number
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Lyophilized Biologics and Vaccines: Modality-Based Approaches
This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide…
- Edition
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- ISBN/ISSN
- 978-1-4939-2383-0
- Collation
- -
- Series Title
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Translational Toxicology
Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and poten…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-27449-2
- Collation
- XV, 380
- Series Title
- Molecular and Integrative Toxicology
- Call Number
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Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug…
The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
- Edition
- 1
- ISBN/ISSN
- 978-1-4471-7032-7
- Collation
- XII, 312
- Series Title
- -
- Call Number
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Toxic Trauma
Winner of BMA Medical Book Award, Highly Commended in Public Health Written for medical professionals, this book provides a concise reference with clear guidelines on how to manage both the victims of chemical agent exposure and the site of the incident. David Baker considers the nature and basic science of the hazards faced as well as the practical management of persons exposed to chemicals a…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-40916-0
- Collation
- XXIII, 238
- Series Title
- -
- Call Number
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Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body.The book is divided into four parts; the first deals with the fundamental principle…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-27596-3
- Collation
- XXII, 483
- Series Title
- Interdisciplinary Applied Mathematics
- Call Number
- -
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