The present work makes use of coarse-grained molecular dynamics simulations and continuum models to investigate the behavior of biomolecules in experiments such as mechanical pulling and driven transport across nanopores. The approach reproduces the wide phenomenology of experiments and allows one to maintain the main features of the transport by modeling the process as a 1D dynamics in a suite…
Sintesis protein bebas sel (cell-free protein synthesis) merupakan teknologi biologi molekuler yang memungkinkan produksi protein secara in vitro tanpa memerlukan sel hidup sebagai sistem ekspresi. Teknologi ini memanfaatkan komponen seluler seperti ribosom, enzim, faktor translasi, asam amino, serta sumber energi untuk mengarahkan proses transkripsi dan translasi sesuai cetakan gen yang diguna…
Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject
Cutaneous malignant melanoma (CMM), which is ranked as the 8th most common cancers in the US, makes 4–7% of skin cancers but it causes approximately 80% of skin cancer deaths. CMM is characterized by insidious and fast progression, heterogenic evolution, and significant resistance to numerous therapeutic strategies. CMM is the result of the uncontrolled proliferation of melanocytes, the cells…
Sekitar dua puluh tahun yang lalu, para peneliti mulai mencari pasangan pengikat protein BCL10 yang dapat mengaktifkan jalur pensinyalan NF-κB. Usaha tersebut pertama kali menemukan protein CARD9, kemudian diikuti tiga protein sejenis lainnya: CARD10 (CARMA3), CARD11 (CARMA1), dan CARD14 (CARMA2). Keempat protein tersebut dikenal sebagai keluarga protein CARMA/CARD dari keempat "kartu" yang me…
Akuaporin adalah keluarga protein saluran membran integral yang sangat terjaga evolusionernya, berfungsi memfasilitasi pergerakan air dan molekul kecil tertentu seperti gliserol, urea, dan amonia secara selektif melintasi membran sel. Tulisan ini mengulas peran dinamis serta mekanisme pengaturan aktivitas akuaporin pada berbagai organisme, mulai dari bakteri, tumbuhan, hingga hewan dan manusia.…
In the textile market industry, technical textiles are one of the fastest growing businesses. Part of that industry consists of textiles for medical and healthcare applications and are responsible for a continuous increase in its market potential [1]. Next to their need in hospital environments, there is a growing demand in other sectors such as the food and hotel industry, due to stricter hygi…
Low-density lipoprotein (LDL) circulating in human bloodstream is the source of lipids that accumulate in arterial intimal cells in atherosclerosis. In-vitro–modified LDL (acetylated, exposed to malondialdehyde, oxidized with transition metal ions, etc.) is atherogenic, that is, it causes accumulation of lipids in cultured cells
Explore a decade of groundbreaking research in "10th Anniversary of Cells—Advances in Plant, Algae, and Fungi Cell Biology." This reprint offers a comprehensive journey into the realms of plant, algae, and fungi cell biology. Delve into the world of genomics, cellular defense mechanisms, mycorrhizal fungi, and the physiology of extremophile algae. A celebration of scientific excellence, this …
Dalam Buku Pegangan Farmakologi Eksperimental tentang “Lipoprotein Kepadatan Tinggi – dari pemahaman biologis hingga eksploitasi klinis”, para penulis yang berkontribusi (anggota dari COST Action BM0904/HDLnet) merangkum dalam lebih dari 20 bab pengetahuan terkini kami tentang struktur, fungsi, metabolisme dan regulasi HDL dalam kesehatan dan beberapa penyakit serta status upaya terapeuti…