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Found 5 from your keywords: subject="Protein Biochemistry,...
cover
The Hsp60 Chaperonin
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Peter Bross

In this unique overview of the Hsp60 chaperonin, Peter Bross addresses molecular biologists, medical research scientists and individuals interested in molecular or general biology. First, Bross discusses the basics of the Hsp60 chaperonin in terms of its structure and the molecular mechanisms determining its function. Second, the author highlights the multiple roles of Hsp60 for cellular system…

Edition
1
ISBN/ISSN
978-3-319-26088-4
Collation
XV, 85,15 b/w illustrations, 4 illustrations in colour
Series Title
SpringerBriefs in Molecular Science
Call Number
-
cover
The Next Generation in Membrane Protein Structure Determination
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MORAES, Isabel

This book reviews current techniques used in membrane protein structural biology, with a strong focus on practical issues. The study of membrane protein structures not only provides a basic understanding of life at the molecular level but also helps in the rational and targeted design of new drugs with reduced side effects. Today, about 60% of the commercially available drugs target membrane p…

Edition
-
ISBN/ISSN
978-3-319-35072-1
Collation
X, 184
Series Title
Advances in Experimental Medicine and Biology
Call Number
-
cover
Large-Scale Quantum-Mechanical Enzymology
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Greg Lever

This work establishes linear-scaling density-functional theory (DFT) as a powerful tool for understanding enzyme catalysis, one that can complement quantum mechanics/molecular mechanics (QM/MM) and molecular dynamics simulations. The thesis reviews benchmark studies demonstrating techniques capable of simulating entire enzymes at the ab initio quantum-mechanical level of accuracy. DFT has trans…

Edition
-
ISBN/ISSN
978-3-319-19351-9
Collation
-
Series Title
-
Call Number
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cover
Kinesins and Cancer
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Frank KozielskiFSB

This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of protei…

Edition
-
ISBN/ISSN
978-94-017-9732-0
Collation
-
Series Title
-
Call Number
-
cover
Intrinsically Disordered Proteins Studied by NMR Spectroscopy
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Isabella C. FelliRoberta Pierattelli

This book discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). The properties of IDPs and IDPRs are highly complementary to those deriving from the presence of a unique and well-defined three-dimensional fold. Ignored for a long time in high-resolution studies of proteins, intrin…

Edition
-
ISBN/ISSN
978-3-319-20164-1
Collation
-
Series Title
-
Call Number
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