Ageing is characterized by the maintaining deterioration of homeostatic processes over time, leading to functional decline and increased risk of disease and death. Several distinct mechanisms underlying ageing have been reported and mounting shreds of evidence have shown that histone methylation, an epigenetic marker, regulates gene expression durin…
As with many other human diseases, oxidative stress is implicated in many neuropsychiatric disorders, including schizophrenia, bipolar disorder, depression and Alzheimer's disease. Due to high oxygen consumption and a lipid-rich environment, the brain is highly susceptible to oxidative stress or redox imbalance. Both increased production of reactive…