The notion that neurons in the living brain can change in response to experience—a phenomenon known as "plasticity"—has become a major conceptual issue in neuroscience research as well as a practical focus for the fields of neural rehabilitation and neurodegenerative disease. Early work dealt with the plasticity of the developing brain and demonstrated the critical role played by sensory ex…
A comprehensive guide to current research, reflecting recent technical breakthroughs that have established the usefulness of the mouse model as part of a bilateral exchange between experimental and clinical research. Recent years have seen a burst of studies on the mouse eye and visual system, fueled in large part by the relatively recent ability to produce mice with precisely defined changes i…