A history of UK radionuclide studies reveals pioneering work from George von Hevesy in Manchester (1911) through to modern PET/MR, with key developments including early homemade scanners (Mallard, Mayneord), GFR measurement, radioimmunoassay, SPECT/CT, and advanced brain imaging (FDG, amyloid). Driven by medical physicists and later clinicians, the field progressed from tracer studies (I-131, T…