This volume thoroughly examines breast cancer stem cells (BCSCs), from basic definitions to techniques for identifying, isolating, culturing, and targeting BCSCs for therapy; there is additional focus on pre-clinical and clinical results. The text begins with a discussion of breast cancer, focusing especially on the limitations of current therapies in its treatment. The subsequent chapters intr…
This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good…
The term “stem cell” appeared in the scientifi c literature as early as 1868 in the work of the eminent German biologist Ernst Haeckel. In this work, Haeckel used the term Stammzelle (“stem cell”) to describe the ancestor unicellular organism from which he presumed all multicellular organisms evolved. Particularly, he also suggested fertilized oocytes as the source giving rise to al…