Malignant biliary obstruction is very difficult to treat; only 10–20% of the patients are suitable for curative resections. Obstructive jaundice is associated with a pro-inflammatory state, altering the normal physiology and affecting multiple organ systems. So, patients with malignant obstructive jaundice are at increased risk of postoperative complications. Nevertheless, the preoperativ…
The incidence of gluten-related disorders (GRDs) continues to increase and its global prevalence is estimated affect to 5% of the population. s. Celiac disease (CD), Dermatitis Herpetiformis (DH), Gluten Ataxia (GA), wheat allergy (WA), and Non-Celiac Gluten Sensitivity (NCGS) are the five major GRDs that present with a wide range of clinical manifestations. They are manifested by symptoms of g…
Pancreatic ductal adenocarcinoma induces systemic inflammatory response (SIR), which can be assessed either by ratios between blood cell counts (neutrophil to lymphocyte ratio, NLR; platelet to lymphocyte ratio, PLR) or concentrations of acute phase proteins, clotting factors and albumins