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Stem Cells in the Lung Development, Repair and Regeneration

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This book presents a comprehensive overview of the current understanding of the organization of endogenous lung stem and progenitor cell compartments during fetal lung development, postnatal lung growth and in adulthood. Progressing stage by stage, the chapters on fetal lung development emphasize the integrated role of epithelial, stromal, vascular and neural cell elements in building a functional lung, while the subsequent chapters on adult lung regeneration describe the nature and properties of adult lung stem/progenitor cells distributed along the proximal-distal axis of the airway tree. The chapters on regulation of lung regeneration and repair discuss how regenerative cells interact with their niche microenvironment and how regulation of lung regeneration and repair in the steady state and following injury recapitulates ontogeny. And, lastly, the chapters on cellular therapies for lung disease and bioengineering the lung focus on promising emerging therapies and approaches in lung regenerative medicine. The scope of this volume of the Stem Cell Biology and Regenerative Medicine series focuses on exploring the topic of building and rebuilding the lung from a cellular rather than amolecular perspective. Thus, the section on cellular therapies does not include extensive coverage of each of the numerous lung diseases, including cancer, which could be amenable to stem cell-based therapies, although the final chapter does include some discussion on the future prospects and challenges. All of the contributors are working on the cutting edge of the lung stem cell field, making this book essential reading for those with an interest in the field of lung stem cell biology and the potential role of cellular therapies and tissue bioengineering approaches in lung regenerative medicine, including biomedical scientists, graduate students, post-graduate researchers and respiratory clinicians.

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Detail Information

Series Title

XIV, 366

Call Number

XIV, 366

Publisher

Springer Cham : Springer Cham., 2015

Collation

-

Language

English

ISBN/ISSN

978-3-319-21082-7

Classification

NONE

Content Type

text

Media Type

computer

Carrier Type

-

Edition

1

Subject(s)

lung regeneration
progenitor cells

Specific Detail Info

-

Statement of Responsibility

van Bertoncello

Other Information

Cataloger

Suwardi

Source

https://link.springer.com/book/10.1007/978-3-319-21082-7

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