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Chapter 4 Deliberating bioethics UNESCO’s standard-setting activities
The sequencing of the entire human genome has opened up unprecedented possibilities for healthcare, but also ethical and social dilemmas about how these can be achieved, particularly in developing countries. UNESCO's Bioethics Programme was established to address such issues in 1993. Since then, it has adopted three declarations on human genetics and bioethics (1997, 2003 and 2005), set up nume…
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- 9780203101797
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Chapter 31 Central Immune Senescence, Reversal Potentials
Ageing is a complex process that affects all living organisms. Senescence is not only conceivable in multicellular organisms, but also in unicellulars. Unlike certain diseases that have specific morbidity rates, ageing is a physiological process that affects all individuals that live long enough (unaffected by i.e. predation or famine) to experience senescence.
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Alternative Crops and Cropping Systems
Alternative crops and cropping systems have importance in whole agricultural sector. As the name suggests, it is an alternative that can currently represent only a small economic importance. On the other hand, in some areas pose a new progressive direction, which has the potential to expand in the future. The goal was to write a book where as many different existing studies as possible could be…
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- 9789535154303
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- 172 hlm; ill., lamp.,
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Alterations of Epigenetics and MicroRNAs in Cancer and Cancer Stem Cell
Studies have shown that alterations of epigenetics and microRNAs (miRNAs) play critical roles in the initiation and progression of human cancer. Epigenetic silencing of tumor suppressor genes in cancer cells is generally mediated by DNA hypermethylation of CpG island promoter and histone modification such as methylation of histone H3 lysine 9 (H3K9) and tri-methylation of H3K27. MiRNAs are smal…
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- 9782889193455
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- 79 hlm; ill., lamp.,
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Advances in Molecular Genetics of Brain Tumors
Deregulation of signalling pathways that regulate cell growth, survival, metabolism, and migration can frequently lead to the progression of cancer. Brain tumours are a large group of malignancies characterised by inter- and intratumoral heterogeneity, with glioblastoma (GBM) being the most aggressive and fatal. The present study aimed to characterise the expression of cancer pathway-relate…
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- 9783036566443
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- 242
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Advances in the Molecular Understanding of Colorectal Cancer
An understanding of the molecular pathogenesis of colorectal cancer by researchers and clinicians is essential to facilitate progress in improving patient outcomes in this common cancer that still carries a poor prognosis if not identified early. This book covers the major areas of importance in the field, incorporating new knowledge that has arisen due to the advancement of molecular technique…
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- 9781839620041
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- oer.unej.ac.id
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The Sweetpotato Genome
This open access book is a compilation of advances in sweetpotato genomics, which have been used to improve our understanding of the evolution of sweetpotato, increase our knowledge of crop growth and development, and provided critical information required for genomic-assisted breeding in sweetpotato. Sweetpotato is a critical food staple for millions of people in the developing world that has…
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- 9783031650031
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- XVII, 166 hlm ill; lamp
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Dilated Cardiomyopathy = From Genetics to Clinical Management
This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents c…
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- 9783030138646
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- IX, 241 ill; hlm
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The Pangenome = Diversity, Dynamics and Evolution of Genomes
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species…
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- 9783030382810
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- XIV, 307 hlm; ill., lamp.,
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Sowing Legume Seeds, Reaping Cash : A Renaissance within Communities in Sub-S…
This open access book shares impact stories – testimonies from various value chain actors who have been part of the Tropical Legumes (TL) projects, over the past twelve years. The Tropical Legumes projects led by ICRISAT in three parts (TLI, TLII and TLIII), constitute a major international initiative supported by the Bill & Melinda Gates Foundation (BMGF) and jointly implemented by the Inter…
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- 9789811508455
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- XVI, 106 hlm; ill., lamp.,
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