Recent achievements in hardware and software developments have enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of data, such as diagnoses, therapies, and human genome data. This book shares the latest research results of applying in-memory data management to personalized medic…
Was, warum, wie, wer und wann? Anhand dieser W-Fragen werden wichtige Methoden und Zusammenhänge zur Planung und Steuerung von Projekten vorgestellt. Das erforderliche Methodenwissen wird dabei praxisorientiert und zugleich theoretisch fundiert auf der Basis jahrelanger Lehrerfahrungen und aktueller Standards vermittelt. Eine Liste der wichtigen Begriffe in deutscher und englischer Sprache am …
This encyclopedia will be an essential resource for our times, reflecting the fact that we currently are living in an expanding data-driven world. Technological advancements and other related trends are contributing to the production of an astoundingly large and exponentially increasing collection of data and information, referred to in popular vernacular as “Big Data.” Social media and c…
This book brings Søren Kierkegaard’s nineteenth-century existentialist project into our contemporary age, applying his understanding of “freedom” and “despair” to science and science studies, queer, decolonial and critical race theory, and disability studies. The book draws out the materialist dimensions of belief, examining the existential dynamics of phenomena like placebos, epigen…
The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, Laszlo Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The series has featured contributions by seven Nobel laureates: D.H.R. Barton, D. Crowfoot Hodgkin, L. Pauling, K. Alder, O. Diels, P. Karrer, H. von Euler-Chelpin. The volumes contain contributi…
Polyploidy – whole-genome duplication (WGD) – is a fundamental driver of biodiversity with significant consequences for genome structure, organization, and evolution. Once considered a speciation process common only in plants, polyploidy is now recognized to have played a major role in the structure, gene content, and evolution of most eukaryotic genomes. In fact, the diversity of eukaryo…
Latest generation sequencing revolutionizes the fields of cancer research and oncology. This follow-up volume focuses more extensively on single cell sequencing of cancer and trials in drug resistance. Another exciting feature is the bioinformatics tools given, that can be used on cancer genome studies. Scientists around the world are attempting to find the root cause of cancer. A reasonable ca…
Soil salinity is a key abiotic-stress and poses serious threats to crop yields and quality of produce. Owing to the underlying complexity, conventional breeding programs have met with limited success. Even genetic engineering approaches, via transferring/overexpressing a single ‘direct action gene’ per event did not yield optimal results. Nevertheless, the biotechnological advents in last d…
This book provides insights into the current state of sorghum genomics. It particularly focuses on the tools and strategies employed in genome sequencing and analysis, public and private genomic resources and how all this information is leading to direct outcomes for plant breeders. The advent of affordable whole genome sequencing in combination with existing cereal functional genomics data has…
This concise handbook provides oncologists and other healthcare providers with crucial updates in the field, including an updated review of the current understanding of the biology of the HER2 pathway, an overview of HER2-testing, and evidence-based discussions of available and emerging HER2-targeted treatment options. An essential clinical text for physicians that screen and treat patients wit…