The first real major breakthrough that laid the basis of HLA antibody detection in the field of solid organ transplantation, came with the introduction of the complement dependent cytotoxicity (CDC) test in 1964 by Terasaki and McClelland. Since then, methods for antibody detection have evolved remarkably from conventional cell-based assays to the current advanced solid phase systems on the Lum…
The main strength of this book is that it examines the challenges facing the field of Bioethics today from medical, ethical and legal perspectives. A critical exchange of ideas from professionals in interdisciplinary fields allows everyone to learn and benefit from the insights gained through others' experiences. Examining, analyzing and understanding these complex medical-ethical-legal issues …
I saggi di questo volume esplorano la complessita? politica, sociale e culturale del rapporto Stati Uniti-Cuba tra Otto e Novecento: esuli cubani che dagli Stati Uniti forgiarono l'indipendenza del loro paese; la profonda trasformazione della societa? cubana durante l'occupazione militare statunitense del 1898-1902; le alleanze ed i conflitti tra femminismo nordamericano e cubano, tra l'identit…
For the past two decades, Sports Medicine has been a burgeoning science in the USA and Western Europe. Great strides have been made in understanding the basic physiology of exercise, energy consumption and the mechanisms of sports injury. Additionally, through advances in minimally invasive surgical treatment and physical rehabilitation, athletes have been returning to sports quicker and at hig…
While the chapters in this book are a long way from solving the enigma that is CFS, they do represent important attempts to understand this complex and perplexing disease. A common theme in them all is CFS as a multisystem disease with the possibility of more than one cause and influenced by a variety of interacting factors. Further, they acknowledge the reality of CFS for persons with this dis…
This book is a collection of theoretical perspectives and research studies from international scholars on neuropsychological aspects of aggression, personality features, gender-based violence, and cultural origins of conflict. Written by experts in the field, it offers insights into multi-theoretical perspectives on aggression and violence and the multifaceted factors involved in the etiology a…
One of the main aims of modern mental health care is to understand a person's explicit and implicit ways of thinking and acting. So, it may seem like the ultimate paradox that mental health care services are currently overflowing with brain concepts belonging to the external, visible brain-world and that neuroscientists are poised to become new experts on human conduct. An Interdisciplinary App…
This open access book examines an interdependent approach to happiness and well-being, one that contrasts starkly with dominant approaches that have originated from Western culture(s). It highlights the diversity of potential pathways towards happiness and well-being globally, and answers calls - voiced in the UN's Sustainable Development Goals - for more socially and environmentally sustainabl…
Monoclonal antibodies and Fc-fusion proteins used clinically are Fc-based therapeutics that grow fastest in the pharmaceutical industry. Since they both contain an Fc fragment, engineering of Fc fragments could be a platform for improving Fc-based drug efficacy. Fc engineering includes various aspects: stabilization of Fc; regulation of effector functions including antibody-dependent cell-media…