Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under v…
This book offers ophthalmologists and medical practitioners a concise, data-driven review of the information that is most relevant in guiding the diagnosis and management of thyroid-associated eye diseases (TED). Thyroid-Associated Eye Disease can be read in its entirety to give a perspective of the field, but also considered as a reference as clinical questions arise. The goal is to deliver …
This book covers the entire spectrum of thyroid diseases in childhood, focusing on the recent advances that have been achieved, from progress in basic science research through to novel or improved approaches to diagnosis and treatment. Introductory chapters discuss thyroid embryogenesis and the role of thyroid hormones in fetal development. The two contrasting forms of thyroid dysfunction, hypo…
This book constitutes revised selected papers from the third ECML PKDD Workshop on Data Analytics for Renewable Energy Integration, DARE 2015, held in Porto, Portugal, in September 2015. The 10 papers presented in this volume were carefully reviewed and selected for inclusion in this book
This brief develops a data collection plan to assess loss related to electrical surges in homes, and explores the potential impact devices that prevent these surges could have in mitigating these losses. Key topics such as surge sources, surge effects and residential surge protection are clearly defined. Recent fire safety codes proposed a requirement that every dwelling unit be fitted with a s…
This book provides a systematic treatment of the mathematical underpinnings of work in data assimilation, covering both theoretical and computational approaches. Specifically the authors develop a unified mathematical framework in which a Bayesian formulation of the problem provides the bedrock for the derivation, development and analysis of algorithms; the many examples used in the text, toget…
Demonstrating the latest research and analysis in the area of through-life engineering services (TES), this book utilizes case studies and expert analysis from an international array of practitioners and researchers – who together represent multiple manufacturing sectors: aerospace, railway and automotive – to maximize reader insights into the field of through-life engineering services. …
Thrombolytic therapy is finally starting to reach patients in a variety of settings all over the world. Formerly in the domain of sub-specialists, thrombolytic therapy now rests in the realm of Emergency Medicine, Intensive Care, Vascular, and Neuro hospital Medicine physicians. Increasingly, non-neurologists use thrombolytic therapy. This is a significant advancement since the 2nd edition to T…
This book provides an up-to-date review of the use of thrombolytic therapy in the treatment of acute pulmonary embolism. It discusses the mechanisms of thrombosis; pharmacokinetics and pharmacodynamics of the most commonly used fibrinolytics; evidence-based results from multicenter control trials in which thrombolytic treatment was administered; criteria by which pulmonary embolism patients req…
This handbook represents a milestone in the progression of Data Envelopment Analysis (DEA). Written by experts who are often major contributors to DEA theory, it includes a collection of chapters that represent the current state-of-the-art in DEA research. Topics include distance functions and their value duals, cross-efficiency measures in DEA, integer DEA, weight restrictions and production t…