This book provides a comprehensive overview on issues surrounding fertility in patients who have been diagnosed with breast cancer or belong to a high-risk population. The impact of breast cancer treatment on fertility is clearly explained and all the available options for fertility preservation are discussed, including the use of assisted reproduction technologies. Guidance is offered on famil…
This volume thoroughly examines breast cancer stem cells (BCSCs), from basic definitions to techniques for identifying, isolating, culturing, and targeting BCSCs for therapy; there is additional focus on pre-clinical and clinical results. The text begins with a discussion of breast cancer, focusing especially on the limitations of current therapies in its treatment. The subsequent chapters intr…
This book presents the current trends and practices in breast imaging. Topics include mammographic interpretation; breast ultrasound; breast MRI; management of the symptomatic breast in young, pregnant and lactating women; breast intervention with imaging pathological correlation; the postoperative breast and current and emerging technologies in breast imaging. It emphasizes the importance of f…
This volume provides a practical yet comprehensive guide to manage the shift in the diagnosis of lung cancer from large resections to small samples, including cytology specimens and core biopsies. Specifically, it outlines various available minimally-invasive modalities and presents algorithms to optimize and maximize sample collection and processing beginning at the time of tissue acquisition …
This book (an updated and extended edition) is about mobilizing women and health care policy makers and providers to unite their efforts in a single strategy for fighting cervical cancer worldwide. The objective of this strategy would be to reverse cervical cancer prevalence and mortality rates among all 2.4 billion women at risk and to achieve this goal within 10-15 years of implementation. Ce…
This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-a…
The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferatio…
This book provides an up-to-date review of recently identified natural anti-tumor compounds from various natural origins including plants, fungi, endophytic fungi and marine organisms. It also includes discussion of new areas such as biotechnology and nanoparticles. Chapters explain the challenges and developments in anti-cancer drug discovery approaches, traditional remedies for prevention an…
Cancer care delivery refers to the multiple layers of the health care system that interact to affect outcomes for patients with cancer and the quality of that care. The factors included in the care delivery system that potentially alter outcomes include social dynamics, financing systems, organizational structures and processes, health technologies, provider and individual behaviors. Because wo…
A wide range of research methods for the study of vascular development, from basic laboratory protocols to advanced technologies used in clinical practice, are covered in this work. A range of methodologies such as molecular imaging platforms and signalling analysis, along with tumour models are collated here. Four sections explore in vitro techniques, in vivo and ex vivo manipulations, imag…